Emulation
- libretro frontend: RetroArch
Nintendo
- NES: Mesen
- SNES: Snes9x
- N64: ares / simple64 or RMG (Mupen64Plus)
- Game Cube + Wii: Dolphin
- GB + GBC + GBA: mGBA
SameBoy is another good emulator for GB + GBC
- DS: melonDS
- Switch: Citron / Ryujinx
PlayStation
- PS1: DuckStation
- PS2
- Android: NethersX2
- PC: PCSX2/LRPS2
- PSP: PPSSPP
Sega
- Saturn: Yaba Sanshiro 2 (Pro)
- Dreamcast: Redream / Flycast